A rapid improved multiplex ligation detection reaction method for the identification of gene mutations in hereditary hearing loss.

Hearing loss (HL) is a common sensory disorder. More than half of HL cases can be attributed to genetic causes. There is no effective therapy for genetic HL at present, early diagnosis to reduce the incidence of genetic HL is important for clinical intervention in genetic HL. Previous studies have i...

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Bibliographic Details
Main Authors: Yalan Liu, Chang Hu, Chang Liu, Deyuan Liu, Lingyun Mei, Chufeng He, Lu Jiang, Hong Wu, Hongsheng Chen, Yong Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215212