Decreased brain and muscle ARNT-like protein 1 expression mediated the contribution of hyperandrogenism to insulin resistance in polycystic ovary syndrome

Decreased brain and muscle ARNT-like protein 1 expression mediated the contribution of hyperandrogenism to insulin resistance in polycystic ovary syndrome

Abstract Background The interface between environmental risk factors and genetic factors could contribute to the pathogenesis of hyperandrogenism and insulin resistance in polycystic ovary syndrome (PCOS); however, the underlying complex mechanism remains to be elucidated. Methods We used dehydroepi...

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Bibliographic Details
Main Authors: Junyu Zhai, Shang Li, Min Hu, Fangfang Di, Jiansheng Liu, Yanzhi Du
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Reproductive Biology and Endocrinology
Subjects:
BMAL1
Hyperandrogenism
Insulin resistance
PCOS
Circadian clock
Online Access:http://link.springer.com/article/10.1186/s12958-020-00592-1

Internet

http://link.springer.com/article/10.1186/s12958-020-00592-1

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