Docking studies reveal zerumbone targets β-catenin of the Wnt-β-catenin pathway in breast cancer

Docking studies reveal zerumbone targets β-catenin of the Wnt-β-catenin pathway in breast cancer

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Breast cancer is the second most common cancer among women worldwide. The Wnt–β-catenin pathway appears to be deregulated in most cancer cells including breast cancer. The role of zerumbone, the active sesquiterpene from Zingiber zerumbet Roscoe, on the Wnt–β-catenin pathway is relatively unknown, e...

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Bibliographic Details
Main Authors: Fatima Ayesha, Abdul Bustamam Ahmad H., Abdullah Rasedee, Karjiban Roghayeh Abedi, Lee Vannajan Sanghiran
Format: Article
Language:English
Published: Serbian Chemical Society 2018-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
zerumbone
Wnt-β-catenin pathway
frizzled (Fzd) protein
β-catenin-transcription factor 4 complex
molecular docking
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2018/0352-51391700108F.pdf

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http://www.doiserbia.nb.rs/img/doi/0352-5139/2018/0352-51391700108F.pdf

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