EAAT2 as a therapeutic research target in Alzheimer's disease: A systematic review

Glutamate is the main excitatory neurotransmitter in the human central nervous system, responsible for a wide variety of normal physiological processes. Glutamatergic metabolism and its sequestration are tightly regulated in the normal human brain, and it has been demonstrated that dysregulation of...

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Bibliographic Details
Main Authors: Oliver W. G. Wood, Jason H. Y. Yeung, Richard L. M. Faull, Andrea Kwakowsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.952096/full