Adaptable functionality of transcriptional feedback in bacterial two-component systems.

A widespread mechanism of bacterial signaling occurs through two-component systems, comprised of a sensor histidine kinase (SHK) and a transcriptional response regulator (RR). The SHK activates RR by phosphorylation. The most common two-component system structure involves expression from a single op...

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Bibliographic Details
Main Authors: J Christian J Ray, Oleg A Igoshin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20168997/?tool=EBI