Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase[S]

Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase[S]

Sphingolipids are vital components of eukaryotic membranes involved in the regulation of cell growth, death, intracellular trafficking, and the barrier function of the plasma membrane (PM). While sphingomyelin (SM) is the major sphingolipid in mammals, previous studies indicate that mammalian cells...

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Bibliographic Details
Main Authors: Philipp Ternes, Jos F.H.M. Brouwers, Joep van den Dikkenberg, Joost C.M. Holthuis
Format: Article
Language:English
Published: Elsevier 2009-11-01
Series:Journal of Lipid Research
Subjects:
bifunctional enzyme
sphingolipid biosynthesis
ceramide homeostasis
cell growth
lipid asymmetry
cervical carcinoma HeLa cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520306933

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http://www.sciencedirect.com/science/article/pii/S0022227520306933

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