Brm inhibits the proliferative response of keratinocytes and corneal epithelial cells to ultraviolet radiation-induced damage.

Brm inhibits the proliferative response of keratinocytes and corneal epithelial cells to ultraviolet radiation-induced damage.

Ultraviolet radiation (UV) from sunlight is the primary cause of skin and ocular neoplasia. Brahma (BRM) is part of the SWI/SNF chromatin remodeling complex. It provides energy for rearrangement of chromatin structure. Previously we have found that human skin tumours have a hotspot mutation in BRM a...

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Bibliographic Details
Main Authors: Nur Mohammad Monsur Hassan, Nicole Painter, C Rolfe Howlett, Andrew W Farrell, Nick Di Girolamo, J Guy Lyons, Gary M Halliday
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4177874?pdf=render

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http://europepmc.org/articles/PMC4177874?pdf=render

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