Near-UV Light Induced ROS Production Initiates Spatial Ca<sup>2+</sup> Spiking to Fire NFATc3 Translocation

Near-UV Light Induced ROS Production Initiates Spatial Ca<sup>2+</sup> Spiking to Fire NFATc3 Translocation

Ca<sup>2+</sup>-dependent gene regulation controls several functions to determine the fate of the cells. Proteins of the nuclear factor of activated T-cells (NFAT) family are Ca<sup>2+</sup> sensitive transcription factors that control the cell growth, proliferation and insul...

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Bibliographic Details
Main Authors: Furkan E. Oflaz, Zhanat Koshenov, Martin Hirtl, Rene Rost, Olaf A. Bachkoenig, Benjamin Gottschalk, Corina T. Madreiter-Sokolowski, Roland Malli, Wolfgang F. Graier
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
UV light
ROS
L-type Ca<sup>2+</sup> channel
transcription factor
NFATc3 translocation
mitochondrial Ca<sup>2+</sup> buffering
Online Access:https://www.mdpi.com/1422-0067/22/15/8189

Internet

https://www.mdpi.com/1422-0067/22/15/8189

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