A sheet pocket to prevent cross-contamination of formalin-fixed paraffin-embedded block for application in next generation sequencing.

A sheet pocket to prevent cross-contamination of formalin-fixed paraffin-embedded block for application in next generation sequencing.

Formalin-fixed paraffin-embedded (FFPE) blocks are used as biomaterials for next-generation sequencing of cancer panels. Cross-contamination is detected in approximately 5% of the DNA extracted from FFPE samples, which reduces the detection rate of genetic abnormalities. There are no effective metho...

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Bibliographic Details
Main Authors: Keiichi Iwaya, Hisae Arai, Nanao Takatou, Yuka Morita, Rinko Ozeki, Hirofumi Nakaoka, Masaru Sakamoto, Tsutomu Kouno, Masayoshi Soma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0266947

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https://doi.org/10.1371/journal.pone.0266947

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