Single-Cell and CellChat Resolution Identifies Collecting Duct Cell Subsets and Their Communications with Adjacent Cells in PKD Kidneys

ADPKD is a genetic disorder with a molecular complexity that remains poorly understood. In this study, we sampled renal cells to construct a comprehensive and spatiotemporally resolved gene expression atlas in whole <i>Pkd1</i> mutant polycystic mouse kidneys at single-cell resolution. W...

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Bibliographic Details
Main Authors: Linda Xiaoyan Li, Xu Zhang, Hongbing Zhang, Ewud Agborbesong, Julie Xia Zhou, James P. Calvet, Xiaogang Li
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/1/45