Natural Killer T Cells Subsets in Cancer, Functional Defects in Prostate Cancer and Implications for Immunotherapy

Natural killer T cells are T lymphocytes with unique activation and effector properties. The majority of NKT cells, termed type-I or iNKT cells, recognize lipid antigens presented on MHC-like CD1d molecules. Type-I NKT cells have the capacity to rapidly secrete various cytokines upon activation, the...

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Bibliographic Details
Main Authors: Michael Nowak, Ingo G.H. Schmidt-Wolf
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/3/3661/