High Dose Intravenous IgG Therapy Modulates Multiple NK Cell and T Cell Functions in Patients With Immune Dysregulation

High Dose Intravenous IgG Therapy Modulates Multiple NK Cell and T Cell Functions in Patients With Immune Dysregulation

Intravenous immunoglobulin (IVIG) is an effective immunomodulatory treatment for immune dysregulation diseases. However, the mechanisms by which it reduces systemic inflammation are not well understood. NK cell cytotoxicity is decreased by IVIG in women with reduced fertility, but IVIG effects on NK...

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Bibliographic Details
Main Authors: Sarah M. McAlpine, Sarah E. Roberts, John J. Heath, Fabian Käsermann, Andrew C. Issekutz, Thomas B. Issekutz, Beata Derfalvi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
IVIG
NK cell
immune dysregulation
Kawasaki disease
autoimmune disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.660506/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.660506/full

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