The Lipid-Modifying Multiple Peptide Resistance Factor Is an Oligomer Consisting of Distinct Interacting Synthase and Flippase Subunits

ABSTRACT  Phospholipids are synthesized at the inner leaflet of the bacterial cytoplasmic membrane but have to be translocated to the outer leaflet to maintain membrane lipid bilayer composition and structure. Even though phospholipid flippases have been proposed to exist in bacteria, only one such...

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Bibliographic Details
Main Authors: Christoph M. Ernst, Sebastian Kuhn, Christoph J. Slavetinsky, Bernhard Krismer, Simon Heilbronner, Cordula Gekeler, Dirk Kraus, Samuel Wagner, Andreas Peschel
Format: Article
Language:English
Published: American Society for Microbiology 2015-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.02340-14