Identification of breast cancer associated variants that modulate transcription factor binding.
Genome-wide association studies (GWAS) have discovered thousands loci associated with disease risk and quantitative traits, yet most of the variants responsible for risk remain uncharacterized. The majority of GWAS-identified loci are enriched for non-coding single-nucleotide polymorphisms (SNPs) an...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-09-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5619690?pdf=render |