Identification of breast cancer associated variants that modulate transcription factor binding.

Genome-wide association studies (GWAS) have discovered thousands loci associated with disease risk and quantitative traits, yet most of the variants responsible for risk remain uncharacterized. The majority of GWAS-identified loci are enriched for non-coding single-nucleotide polymorphisms (SNPs) an...

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Bibliographic Details
Main Authors: Yunxian Liu, Ninad M Walavalkar, Mikhail G Dozmorov, Stephen S Rich, Mete Civelek, Michael J Guertin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5619690?pdf=render