PRKN regulates inner mitochondrial membrane PHB2 during mitophagy

PINK1 (PTEN induced kinase 1) and PRKN-mediated mitophagy is an important mitochondrial quality control pathway which selectively degrades damaged mitochondria and is tightly associated with neurodegenerative diseases, including Parkinson disease and amyotrophic lateral sclerosis. The current model...

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Bibliographic Details
Main Authors: Shan Sun, Hongfeng Wang, Qilian Ma, Ningning Li, Mian Cao, Kin Yip Tam, Zheng Ying
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Autophagy Reports
Subjects:
Online Access:http://dx.doi.org/10.1080/27694127.2022.2164643