Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1

Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1

The accumulation of 3' untranslated region (3'-UTR), AU-rich element (ARE) containing mRNAs, are predominantly controlled at the post-transcriptional level. Regulation appears to rely on a variable and dynamic interaction between mRNA target and ARE-specific binding proteins (AUBPs). The A...

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Bibliographic Details
Main Authors: Zhong-Jian Shen, James S. Malter
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Biomolecules
Subjects:
AU-rich element
phosphorylation
prolyl isomerase Pin1
RNA-binding protein
signaling
gene regulation
mRNA turnover
kinase
Online Access:http://www.mdpi.com/2218-273X/5/2/412

Internet

http://www.mdpi.com/2218-273X/5/2/412

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