Hierarchical length and sequence preferences establish a single major piRNA 3′-end
Summary: PIWI-interacting RNAs (piRNAs) guard germline genomes against the deleterious action of mobile genetic elements. PiRNAs use extensive base-pairing to recognize their targets and variable 3′ends could change the specificity and efficacy of piRNA silencing. Here, we identify conserved rules t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-06-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004222006988 |