Machine learning algorithm predicts fibrosis-related blood diagnosis markers of intervertebral disc degeneration

Machine learning algorithm predicts fibrosis-related blood diagnosis markers of intervertebral disc degeneration

Abstract Background Intervertebral disc cell fibrosis has been established as a contributing factor to intervertebral disc degeneration (IDD). This study aimed to identify fibrosis-related diagnostic genes for patients with IDD. Methods RNA-sequencing data was downloaded from Gene Expression Omnibus...

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Bibliographic Details
Main Authors: Wei Zhao, Jinzheng Wei, Xinghua Ji, Erlong Jia, Jinhu Li, Jianzhong Huo
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Medical Genomics
Subjects:
Intervertebral disc degeneration
Fibrosis
Diagnostic genes
GSEA
Immune Infiltration
Regulatory network
Online Access:https://doi.org/10.1186/s12920-023-01705-6

Internet

https://doi.org/10.1186/s12920-023-01705-6

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