Dendritic diameters affect the spatial variability of intracellular calcium dynamics in computer models

Dendritic diameters affect the spatial variability of intracellular calcium dynamics in computer models

There is growing interest in understanding calcium dynamics in dendrites, both experimentally and computationally. Many processes influence these dynamics, but in dendrites there is a strong contribution of morphology because the peak calcium levels are strongly determined by the surface to volume r...

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Bibliographic Details
Main Authors: Haroon eAnwar, Christopher J. Roome, Hermina eNedelescu, Weiliang eChen, Bernd eKuhn, Erik eDe Schutter
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Diffusion
compartmentalization
morphology
intracellular calcium
active dendrites
calcium buffering
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00168/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00168/full

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