DNA hypomethylation drives changes in MAGE-A gene expression resulting in alteration of proliferative status of cells

Abstract Melanoma Antigen Genes (MAGEs) are a family of genes that have piqued the interest of scientists for their unique expression pattern. A subset of MAGEs (Type I) are expressed in spermatogonial cells and in no other somatic tissue, and then re-expressed in many cancers. Type I MAGEs are ofte...

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Bibliographic Details
Main Authors: Ashley Colemon, Taylor M. Harris, Saumya Ramanathan
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Genes and Environment
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41021-020-00162-2