DNA hypomethylation drives changes in MAGE-A gene expression resulting in alteration of proliferative status of cells
Abstract Melanoma Antigen Genes (MAGEs) are a family of genes that have piqued the interest of scientists for their unique expression pattern. A subset of MAGEs (Type I) are expressed in spermatogonial cells and in no other somatic tissue, and then re-expressed in many cancers. Type I MAGEs are ofte...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
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Series: | Genes and Environment |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s41021-020-00162-2 |