The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss

The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss

Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells against cisplatin-induced apoptosis. In the current...

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Bibliographic Details
Main Authors: Sumana Ghosh, Sandeep Sheth, Kelly Sheehan, Debashree Mukherjea, Asmita Dhukhwa, Vikrant Borse, Leonard P. Rybak, Vickram Ramkumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
endocannabinoids
CB2 receptor
cisplatin
hearing loss
ribbon synapse
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00271/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00271/full

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