DrImpute: imputing dropout events in single cell RNA sequencing data
Abstract Background The single cell RNA sequencing (scRNA-seq) technique begin a new era by allowing the observation of gene expression at the single cell level. However, there is also a large amount of technical and biological noise. Because of the low number of RNA transcriptomes and the stochasti...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-06-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2226-y |