An In-Silico Sequence-Structure-Function Analysis of the N-Terminal Lobe in CT Group Bacterial ADP-Ribosyltransferase Toxins

The C3-like toxins are single-domain proteins that represent a minimal mono-ADP-ribosyl transferase (mART) enzyme with a simple model scaffold for the entire cholera toxin (CT)-group. These proteins possess a single (A-domain) that modifies Rho proteins. In contrast, C2-like toxins require a binding...

Full description

Bibliographic Details
Main Authors: Miguel R. Lugo, A. Rod Merrill
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/6/365