An In-Silico Sequence-Structure-Function Analysis of the N-Terminal Lobe in CT Group Bacterial ADP-Ribosyltransferase Toxins
The C3-like toxins are single-domain proteins that represent a minimal mono-ADP-ribosyl transferase (mART) enzyme with a simple model scaffold for the entire cholera toxin (CT)-group. These proteins possess a single (A-domain) that modifies Rho proteins. In contrast, C2-like toxins require a binding...
Main Authors: | Miguel R. Lugo, A. Rod Merrill |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-06-01
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Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/11/6/365 |
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