Analyzing cachectic phenotypes in the muscle and fat body of Drosophila larvae

Summary: Drosophila has become a popular model for examining the metabolic wasting syndrome, cachexia, characterized by degradation of muscles and fat. Here we present a protocol for quick and consistent scoring of muscle detachment, fat body lipid droplet size, and extracellular matrix (ECM) quanti...

Full description

Bibliographic Details
Main Authors: Callum Dark, Shane Cheung, Louise Y. Cheng
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722001101