Dengue virus 4/2 envelope domain chimeric virus panel maps type-specific responses against dengue serotype 2

Dengue virus 4/2 envelope domain chimeric virus panel maps type-specific responses against dengue serotype 2

ABSTRACT The DENV envelope (E) and pre-membrane (prM) glycoproteins are primary targets of serologic immunity after infection and vaccination. Of these, serotype-specific (TS) antibodies typically target E domains, while serotype cross-reactive (CR) antibodies typically the target prM protein and co...

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Bibliographic Details
Main Authors: Deanna R. Zhu, Alecia J. Rajesh, Rita M. Meganck, Ellen F. Young, Jennifer E. Munt, Victor L. Tse, Boyd Yount, Helen Conrad, Laura White, Sandra Henein, Aravinda M. DeSilva, Ralph S. Baric
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
dengue
neutralizing antibodies
reverse genetics
Online Access:https://journals.asm.org/doi/10.1128/mbio.00818-23

Internet

https://journals.asm.org/doi/10.1128/mbio.00818-23

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