Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis drug resistance in South Africa: a retrospective molecular epidemiology study

Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis drug resistance in South Africa: a retrospective molecular epidemiology study

Summary: Background: South Africa has a high burden of rifampicin-resistant tuberculosis (including multidrug-resistant [MDR] tuberculosis), with increasing rifampicin-monoresistant (RMR) tuberculosis over time. Resistance acquisition during first-line tuberculosis treatment could be a key contribu...

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Main Authors: Helen Cox, ProfPhD, Zubeida Salaam-Dreyer, PhD, Galo A Goig, PhD, Mark P Nicol, ProfPhD, Fabrizio Menardo, PhD, Anzaan Dippenaar, PhD, Erika Mohr-Holland, MPH, Johnny Daniels, BA, Patrick G T Cudahy, PhD, Sonia Borrell, PhD, Miriam Reinhard, MD, Anna Doetsch, MSc, Christian Beisel, PhD, Anja Reuter, MD, Jennifer Furin, MD, Sebastien Gagneux, ProfPhD, Robin M Warren, ProfPhD
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:The Lancet Microbe
Online Access:http://www.sciencedirect.com/science/article/pii/S2666524721001440

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http://www.sciencedirect.com/science/article/pii/S2666524721001440

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