Ozone alleviates MSU-induced acute gout pain via upregulating AMPK/GAS6/MerTK/SOCS3 signaling pathway

Ozone alleviates MSU-induced acute gout pain via upregulating AMPK/GAS6/MerTK/SOCS3 signaling pathway

Abstract Background Gout pain seriously affects the quality of patients' life. There is still no effective treatment. The inflammatory response is the main mechanism of gout. Here, we found that ozone can reduce the inflammatory reaction in the joints of gouty mice and relieve gout pain, and we...

Full description

Bibliographic Details
Main Authors: Wen Fan, Chong Liu, Dacai Chen, Chenjie Xu, Xiuting Qi, Ailin Zhang, Xuexian Zhu, Yujie Liu, Lei Wang, Lanxiang Hao, Wen-Tao Liu, Liang Hu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Translational Medicine
Subjects:
Ozone
AMPK
Gas 6
MerTK
SOCS3
MMP9
Online Access:https://doi.org/10.1186/s12967-023-04769-1

Internet

https://doi.org/10.1186/s12967-023-04769-1

Similar Items