The Cytolytic Activity of Vaginolysin Strictly Depends on Cholesterol and Is Potentiated by Human CD59

Gardnerella vaginalis produces cytolysin vaginolysin (VLY), which has been suggested to be a contributor to bacterial vaginosis pathogenesis. VLY along with intermedilysin (ILY) from Streptococcus intermedius have been attributed to a group of cholesterol-dependent cytolysins (CDCs) whose pore-formi...

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Bibliographic Details
Main Authors: Milda Zilnyte, Česlovas Venclovas, Aurelija Zvirbliene, Milda Pleckaityte
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/1/110