Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain

<p>Abstract</p> <p>Background</p> <p>AMP-activated protein kinase (AMPK) is a known physiological cellular energy sensor and becomes phosphorylated at Thr-172 in response to changes in cellular ATP levels. Activated AMPK acts as either an inducer or suppressor of apopto...

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Bibliographic Details
Main Authors: Chiles Thomas C, Blair Derek, Marsh Jeremy, Mulrooney Tiernan J, Mukherjee Purna, Seyfried Thomas N
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/37