Stem cell properties of human clonal salivary gland stem cells are enhanced by three-dimensional priming culture in nanofibrous microwells

Stem cell properties of human clonal salivary gland stem cells are enhanced by three-dimensional priming culture in nanofibrous microwells

Abstract Background Three-dimensional (3D) cultures recapitulate the microenvironment of tissue-resident stem cells and enable them to modulate their properties. We determined whether salivary gland-resident stem cells (SGSCs) are primed by a 3D spheroid culture prior to treating irradiation-induced...

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Bibliographic Details
Main Authors: Hyun-Soo Shin, Songyi Lee, Hye Jin Hong, Young Chang Lim, Won-Gun Koh, Jae-Yol Lim
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Stem Cell Research & Therapy
Subjects:
Salivary glands
Xerostomia
Spheroid
Micropatterned nanofibrous scaffolds
Wnt
Online Access:http://link.springer.com/article/10.1186/s13287-018-0829-x

Internet

http://link.springer.com/article/10.1186/s13287-018-0829-x

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