Does Cancer of Unknown Primary (CUP) Truly Exist as a Distinct Cancer Entity?

Does Cancer of Unknown Primary (CUP) Truly Exist as a Distinct Cancer Entity?

Cancer of unknown primary (CUP) designates an enigmatic cancer entity with histologic confirmation of malignancy from a metastasis but no identifiable primary tumor in spite of a thorough diagnostic work-up. In this review, we discuss the validity of CUP as a distinct cancer entity as well as diagno...

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Bibliographic Details
Main Authors: Tilmann Bochtler, Alwin Krämer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
Cancer of unknown primary (CUP)
metastasis
classifier assay
chromosomal instability (CIN)
next generation sequencing
clonal relationship
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00402/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00402/full

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