Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD

Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD

In area CA1 of the hippocampus, long-term depression (LTD) can be induced by activating group I metabotropic glutamate receptors (mGluRs), with the selective agonist DHPG. There is evidence that mGluR-LTD can be expressed by either a decrease in the probability of neurotransmitter release [P(r)] or...

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Bibliographic Details
Main Authors: Thomas M. Sanderson, Liam T. Ralph, Mascia Amici, Ai Na Ng, Bong-Kiun Kaang, Min Zhuo, Sang Jeong Kim, John Georgiou, Graham L. Collingridge
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
long-term depression (LTD)
metabotropic glutamate (mGlu) receptor
DHPG
hippocampus
CA1
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2022.857675/full

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https://www.frontiersin.org/articles/10.3389/fnsyn.2022.857675/full

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