Activation of Glutamate Transporter-1 (GLT-1) Confers Sex-Dependent Neuroprotection in Brain Ischemia

Activation of Glutamate Transporter-1 (GLT-1) Confers Sex-Dependent Neuroprotection in Brain Ischemia

Stroke is one of the leading causes of long-term disability. During ischemic stroke, glutamate is released, reuptake processes are impaired, and glutamate promotes excitotoxic neuronal death. Astrocytic glutamate transporter 1 (GLT-1) is the major transporter responsible for removing excess glutamat...

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Bibliographic Details
Main Authors: Flavia A. Tejeda-Bayron, David E. Rivera-Aponte, Christian J. Malpica-Nieves, Gerónimo Maldonado-Martínez, Héctor M. Maldonado, Serguei N. Skatchkov, Misty J. Eaton
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Brain Sciences
Subjects:
glutamate
glial cells
brain ischemia
cerebrovascular disease/stroke
sex-specific
glutamate transporters
Online Access:https://www.mdpi.com/2076-3425/11/1/76

Internet

https://www.mdpi.com/2076-3425/11/1/76

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