Synthesis and Structure–Activity Relationship of Thiourea Derivatives Against <i>Leishmania amazonensis</i>

Synthesis and Structure–Activity Relationship of Thiourea Derivatives Against <i>Leishmania amazonensis</i>

<b>Background:</b> Leishmaniasis, caused by <i>Leishmania</i> protozoa and transmitted by vectors, presents varied clinical manifestations based on parasite species and host immunity. The lack of effective vaccines or treatments has prompted research into new therapies, inclu...

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Bibliographic Details
Main Authors: Gil Mendes Viana, Edézio Ferreira da Cunha-Junior, Paloma Wetler Meireles Carreiros Assumpção, Marianne Grilo Rezende, Yago Sousa dos Santos Emiliano, Laiza Maria da Silva Soares, Gabriel Rodrigues Coutinho Pereira, Carlos Rangel Rodrigues, Lucio Mendes Cabral, Eduardo Caio Torres-Santos
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
thiourea derivatives
leishmaniasis
<i>Leishmania amazonensis</i>
medicinal chemistry
SARs
drug discovery
Online Access:https://www.mdpi.com/1424-8247/17/12/1573

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https://www.mdpi.com/1424-8247/17/12/1573

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