Serotonin Activates Bacterial Quorum Sensing and Enhances the Virulence of Pseudomonas aeruginosa in the Host

Serotonin Activates Bacterial Quorum Sensing and Enhances the Virulence of Pseudomonas aeruginosa in the Host

Bacteria in humans play an important role in health and disease. Considerable emphasis has been placed in understanding the role of bacteria in host-microbiome interkingdom communication. Here we show that serotonin, responsible for mood in the brain and motility in the gut, can also act as a bacter...

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Bibliographic Details
Main Authors: Leslie D. Knecht, Gregory O'Connor, Rahul Mittal, Xue Z. Liu, Pirouz Daftarian, Sapna K. Deo, Sylvia Daunert
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:EBioMedicine
Subjects:
Host-microbiome interactions
Interkingdom signaling molecule
Las pathway
Pseudomonas aeruginosa
N-acyl homoserine lactone
Quorum sensing
Serotonin
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416302390

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http://www.sciencedirect.com/science/article/pii/S2352396416302390

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