Integrating Extracellular Flux Measurements and Genome-Scale Modeling Reveals Differences between Brown and White Adipocytes

Integrating Extracellular Flux Measurements and Genome-Scale Modeling Reveals Differences between Brown and White Adipocytes

White adipocytes are specialized for energy storage, whereas brown adipocytes are specialized for energy expenditure. Explicating this difference can help identify therapeutic targets for obesity. A common tool to assess metabolic differences between such cells is the Seahorse Extracellular Flux (XF...

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Bibliographic Details
Main Authors: Alfred K. Ramirez, Matthew D. Lynes, Farnaz Shamsi, Ruidan Xue, Yu-Hua Tseng, C. Ronald Kahn, Simon Kasif, Jonathan M. Dreyfuss
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Subjects:
metabolic flux analysis
flux balance analysis
white adipose tissue
brown adipose tissue
extracellular flux analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717317175

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http://www.sciencedirect.com/science/article/pii/S2211124717317175

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