Inhibitory Effects of Fosmidomycin Against Babesia microti in vitro

Inhibitory Effects of Fosmidomycin Against Babesia microti in vitro

Babesia microti, the main pathogen causing human babesiosis, has been reported to exhibit resistance to the traditional treatment of azithromycin + atovaquone and clindamycin + quinine, suggesting the necessity of developing new drugs. The methylerythritol 4-phosphate (MEP) pathway, a unique pathway...

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Bibliographic Details
Main Authors: Sen Wang, Muxiao Li, Xiaoying Luo, Long Yu, Zheng Nie, Qin Liu, Xiaomeng An, Yangsiqi Ao, Jiaxu Chen, Yu Tian, Junlong Zhao, Lan He
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Babesia microti
fosmidomycin
DXR
isoprenoid
babesiosis
methylerythritol 4-phosphate
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00247/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00247/full

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