Synthesis and Biological Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Containing a Phenylalanine Moiety

Synthesis and Biological Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Containing a Phenylalanine Moiety

New 1,3,4-thiadiazole, 6, 7 and 1,2,4-triazole derivatives, 8, 9 containing a phenylalanine moiety have been synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazides, 4, 5, in acid and alkaline media, respectively; the thiosemicarbazides were obtained by reaction of hydrazid...

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Bibliographic Details
Main Authors: Cristian Peptu, Jacques Desbrieres, Marcel Popa, Valeriu Sunel, Lenuta Profire, Mihaela Moise
Format: Article
Language:English
Published: MDPI AG 2009-07-01
Series:Molecules
Subjects:
phenylalanine
thiosemicarbazide
1
3
4-thiadiazole
2
4-triazole
anti-inflammatory activity
Online Access:http://www.mdpi.com/1420-3049/14/7/2621/

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http://www.mdpi.com/1420-3049/14/7/2621/

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