Injectable sustained‐release poly(lactic‐co‐glycolic acid) (PLGA) microspheres of exenatide prepared by supercritical fluid extraction of emulsion process based on a design of experiment approach

Injectable sustained‐release poly(lactic‐co‐glycolic acid) (PLGA) microspheres of exenatide prepared by supercritical fluid extraction of emulsion process based on a design of experiment approach

Abstract This study aimed to develop an improved sustained‐release (SR) PLGA microsphere of exenatide using supercritical fluid extraction of emulsions (SFEE). As a translational research, we investigated the effect of various process parameters on the fabrication of exenatide‐loaded PLGA microspher...

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Bibliographic Details
Main Authors: Heejun Park, Eun‐Sol Ha, Jeong‐Soo Kim, Min‐Soo Kim
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Bioengineering & Translational Medicine
Subjects:
Box–Behnken design
exenatide
pharmacodynamic
pharmacokinetic
PLGA microspheres
supercritical fluid extraction of emulsions
Online Access:https://doi.org/10.1002/btm2.10485

Internet

https://doi.org/10.1002/btm2.10485

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