Assessment of glutathione S-transferaseM1 (GSTM1) and its polymorphisms GSTM1 null in the response to treatment with chemotherapy in advanced ovarian carcinoma

Assessment of glutathione S-transferaseM1 (GSTM1) and its polymorphisms GSTM1 null in the response to treatment with chemotherapy in advanced ovarian carcinoma

Objective: To assess if the genotype of the glutathione S-transferaseM1 (GSTM1) enzyme and its GSTM1 null polymorphism can influencethe response to chemotherapeutic treatment of advanced ovariancancer. Methods: Case-control study of 112 patients with advancedovarian cancer submitted to chemotherapy...

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Bibliographic Details
Main Authors: Gilberto Kendi Takeda, Daniela Batista Leite, Michele Gilvana Junqueira, Luiz Augusto Freire Lopes, Ismael Dale Cotrim Guerreiro da Silva, Fausto Farah Baracat
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2011-09-01
Series:Einstein (São Paulo)
Subjects:
Ovarian neoplasms/drug therapy
Polymorphism
genetic
Glutathione transferase
Online Access:http://apps.einstein.br/revista/arquivos/PDF/1872-Einstein_v9n3_367-371_ingles.pdf

Internet

http://apps.einstein.br/revista/arquivos/PDF/1872-Einstein_v9n3_367-371_ingles.pdf

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