Clinical significance of the CCR5delta32 allele in hepatitis C.

BACKGROUND:The CCR5 receptor, expressed on Th1 cells, may influence clinical outcomes of HCV infection. We explored a possible link between a CCR5 32-base deletion (CCR5delta32), resulting in the expression of a non-functioning receptor, and clinical outcomes of HCV infection. METHODS:CCR5 and HCV-r...

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Main Authors: Isabelle Morard, Sophie Clément, Alexandra Calmy, Alessandra Mangia, Andrea Cerny, Andrea De Gottardi, Meri Gorgievski, Markus Heim, Raffaele Malinverni, Darius Moradpour, Beat Müllhaupt, David Semela, Stéphanie Pascarella, Pierre-Yves Bochud, Franco Negro, Swiss Hepatitis C Cohort Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4156365?pdf=render