A Zinc-Dependent Metalloproteinase of Brucella abortus Is Required in the Intracellular Adaptation of Macrophages

A Zinc-Dependent Metalloproteinase of Brucella abortus Is Required in the Intracellular Adaptation of Macrophages

Brucella abortus is a pathogen that survives in macrophages. Several virulence factors participate in this process, including the open reading frame (ORF) BAB1_0270 codifying for a zinc-dependent metalloproteinase (ZnMP). Here, its contribution in the intracellular adaptation of B. abortus was analy...

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Bibliographic Details
Main Authors: Leonardo A. Gómez, Francisco I. Alvarez, Raúl E. Molina, Rodrigo Soto-Shara, Carla Daza-Castro, Manuel R. Flores, Yrvin León, Angel A. Oñate
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
Subjects:
host-pathogen interaction
virulence
attenuation
toxin-anti-toxin systems
gene regulation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01586/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01586/full

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