Garcinol A Novel Inhibitor of Platelet Activation and Apoptosis

Garcinol A Novel Inhibitor of Platelet Activation and Apoptosis

Garcinol, an anti-inflammatory and anti-carcinogenic polyisoprenylated benzophenone isolated from Garcinia plants, stimulates tumor cell apoptosis and suicidal erythrocyte death, but supports the survival of hepatocytes and neurons. The present study explored whether the substance influences platele...

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Bibliographic Details
Main Authors: Hang Cao, Abdulla Al Mamun Bhuyan, Anja T. Umbach, Ke Ma, Oliver Borst, Meinrad Gawaz, Shaqiu Zhang, Bernd Nürnberg, Florian Lang
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Toxins
Subjects:
CRP
platelet activation
degranulation
integrin
cytosolic Ca<sup>2+</sup> concentration
caspase
phosphatidylserine translocation
Online Access:https://www.mdpi.com/2072-6651/11/7/382

Internet

https://www.mdpi.com/2072-6651/11/7/382

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