Baculovirus displaying SARS-CoV-2 spike RBD promotes neutralizing antibody production in a mouse model
Abstract Background There is always a need for a safe and efficient vaccine platform, especially when facing a pandemic such as COVID-19. Most of the SARS-CoV-2-based vaccines are based on the full spike protein, which is presented as a trimerized protein, and many viral vector vaccines express the...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2023-02-01
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Series: | Journal of Genetic Engineering and Biotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s43141-023-00472-2 |