Baculovirus displaying SARS-CoV-2 spike RBD promotes neutralizing antibody production in a mouse model

Abstract Background There is always a need for a safe and efficient vaccine platform, especially when facing a pandemic such as COVID-19. Most of the SARS-CoV-2-based vaccines are based on the full spike protein, which is presented as a trimerized protein, and many viral vector vaccines express the...

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Bibliographic Details
Main Authors: Mohamed A. Wahba, Dina Mofed, Doaa A. Ghareeb, Jihad I. Omran, Tamer Z. Salem
Format: Article
Language:English
Published: SpringerOpen 2023-02-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s43141-023-00472-2