Increased antigen specific T cell numbers in the absence of altered migration or division rates as a result of mucosal cholera toxin administration.

Cholera toxin (CT) is a mucosal adjuvant capable of inducing strong immune responses to co-administered antigens following oral or intranasal immunization of mice. To date, the direct effect of CT on antigen-specific CD4(+) T cell migration and proliferation profiles in vivo is not well characterize...

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Bibliographic Details
Main Authors: Maria Kaparakis-Liaskos, Michelle D Tate, Jason D Price, Martin Pearse, Odilia L C Wijburg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3609821?pdf=render