Probabilistic edge inference of gene networks with markov random field-based bayesian learning

Current algorithms for gene regulatory network construction based on Gaussian graphical models focuses on the deterministic decision of whether an edge exists. Both the probabilistic inference of edge existence and the relative strength of edges are often overlooked, either because the computational...

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Bibliographic Details
Main Authors: Yu-Jyun Huang, Rajarshi Mukherjee, Chuhsing Kate Hsiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1034946/full