Association Between Genetic Variant in the Promoter of Pri-miR-34b/c and Risk of Glioma

Growing evidence indicates that p53 can regulate the expression of miRNAs, particularly the miR-34 family members, which are described as potential tumor suppressors. Loss of miR-34 suppresses TP53-mediated cell death, whereas over expression of miR-34 induced apoptosis. The study designed to invest...

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Bibliographic Details
Main Authors: Jinghui Li, Xiaoyu Liu, Yu Qiao, Renli Qi, Shunjin Liu, Jing Guo, Yang Gui, Juanjuan Li, Hualin Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00413/full