Chronic kidney disease promotes cerebral microhemorrhage formation

Chronic kidney disease promotes cerebral microhemorrhage formation

Abstract Background Chronic kidney disease (CKD) is increasingly recognized as a stroke risk factor, but its exact relationship with cerebrovascular disease is not well-understood. We investigated the development of cerebral small vessel disease using in vivo and in vitro models of CKD. Methods CKD...

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Bibliographic Details
Main Authors: Chuo Fang, Wei Ling Lau, Jiahong Sun, Rudy Chang, Adrian Vallejo, Donghy Lee, Jihua Liu, Han Liu, Yu-Han Hung, Yitong Zhao, Annlia Paganini-Hill, Rachita K. Sumbria, David H. Cribbs, Mark Fisher
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Neuroinflammation
Subjects:
Cerebral microhemorrhages/microbleeds
Aging
Chronic kidney disease
Microglial activation
Brain endothelial cells
Blood–brain barrier
Online Access:https://doi.org/10.1186/s12974-023-02703-2

Internet

https://doi.org/10.1186/s12974-023-02703-2

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