Metabolic enzyme clustering by coiled coils improves the biosynthesis of resveratrol and mevalonate

Metabolic enzyme clustering by coiled coils improves the biosynthesis of resveratrol and mevalonate

Abstract The clustering of biosynthetic enzymes is used in nature to channel reaction products and increase the yield of compounds produced by multiple reaction steps. The coupling of multiple enzymes has been shown to increase the biosynthetic product yield. Different clustering strategies have par...

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Bibliographic Details
Main Authors: Tina Fink, Bojana Stevović, René Verwaal, Johannes A. Roubos, Rok Gaber, Mojca Benčina, Roman Jerala, Helena Gradišar
Format: Article
Language:English
Published: SpringerOpen 2020-05-01
Series:AMB Express
Subjects:
Designed coiled-coil dimers
Enzyme clustering
Biosynthesis
Resveratrol
Mevalonate
Online Access:http://link.springer.com/article/10.1186/s13568-020-01031-5

Internet

http://link.springer.com/article/10.1186/s13568-020-01031-5

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